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What is Skinvive?

SKINVIVE™ by JUVÉDERM® helps the skin retain its natural moisture and softness leading to an improvement in the skin smoothness of the cheeks.

In clinical studies, patients who were treated with SKINVIVE™ by JUVÉDERM® also reported high satisfaction with how glowing, hydrated, refreshed, and healthy their skin looked through 6 months.

How Skinvive works

You may have seen hyaluronic acid as an ingredient in moisturizing creams or serums. The modified hyaluronic acid (HA) in SKINVIVE by JUVÉDERM® keeps your skin hydrated, looking healthy, and glowing.*

The modified hyaluronic acid (HA) in SKINVIVE by JUVÉDERM® improves cheek skin smoothness, and helps skin look hydrated, healthy, and glowing. In clinical studies, patients who were treated with SKINVIVE by JUVÉDERM® reported high satisfaction with how glowing, hydrated, refreshed, and healthy their skin looked.

What to expect during your treatment

  • Multiple microdroplet injections—where a tiny amount of product is injected just below the skin—are performed on each cheek by a specialist
  • During your appointment, your licensed specialist should explain the procedure and provide after-care directions
  • Lidocaine, a common pain reliever (you get it at the dentist), is an ingredient in SKINVIVE™ by JUVÉDERM® to keep you comfortable
  • Minimize strenuous exercise, exposure to extensive sun or heat, and alcoholic beverages within the first 24 hours following treatment

Important Safety Information


SKINVIVE” by JUVEDERM” injectable gel is indicated for intradermal injection to improve silen amocthnesa of the checks in adults over the age of 21.



This product should not be used in patients who have severe allergies, marked by a history of anaphylaxis or history or presence of multiple severe allergies, and should not be used in patients with a history of allergies to Gram-positive bacterial proteins or lidocaine contained in this product.


  • Do not inject into blood vessels. Introduction of this product into the vasculature may lead to embolization, occlusion of the vessels, ischemia, or infarction. Take extra care when injecting soft-bissue fliers; for example, after insertion of the needle and just before injection, the plunger rod can be withdrawn slightly to aspirate and verify the needle is not intravascular, inject the product slowly. and apply the least amount of pressure necessary. Rare, but serious, adverse events associated with the intravascular Injection of soft-tissue fillers in the face have been reported and Include temporary or permanent vision impairment, bindness, cerebral ischemia or cerebral hemorrhage leading to stroke, skin necrosis, and damage to underlying facial structures. Immediately atop the injection if a patient exhibits any of the following symptoms: changes in vision, signs of a stroke, blanching of the skin, unusual pain during or shortly after the procedure. Patients should receive prompt medical attention and, possibly, evalustion by an appropriate healthcare professional specisist should an intravascular injection occur
  • Product use at specifio sites in which an active inflammatory process [skin eruptions such as cysts. pimples, rashes, or hives) or infection is present should be deferred until the underlying process has been controlled
  • Injection site responses consist mainly of short-term inflammatory symptoms and generally resolve within 1 week. Refer to the ADVERSE EVENTS


  • To minimize the risk of potential complications, this product should orly be used by healthcare professionals who have appropriate training, experience, and who are knowiedgeable about the anatomy at and around the site of injection
  • Discuss all potential risks of soft tissue injections with patients prior to treatment and ensure patients are aware of signs and symptoms of potential complications
  • Limit patients to 20 mL of any JUVÉDERM’ injectable gel per 60 kg (130 Ibs.) body mass per year. The safety of injecting greater amounts has not been established
  • This product is intended for improving skin amocthness and fine lines of the cheeks. The safety and effectiveness of use in other areas of the body have not been established
  • Injection of more than 6.0 mL of this product (initial and touch-up treatment combined) for improvement of sin smoothness and fine lines of the cheeks has not been studied
  • As with all transcutaneous procedures, injections of the product carry a risk of infection
  • The safety for use during pregnancy, in breastfeeding females, and in patients under 22 years has not been established
  • The safety in patients with known susceptibility to keloid formation, hypertrophic scarring, or pigmentation disorders has not been studied
    This product should be used with caution in patients on immunosuppressive therapy
  • Patients taking medications that can prolong bleeding (such as aspirin, nonsteroidsl anti-inflammatory drugs, and warfarin) may experience increased bruising or bleeding at treatment sites
  • Patients may experience late onset AEs with use of injectable gel implants, including this product
  • This product should only be used by healthcare professionals who have appropriate experience and who are knowledgeable about the anatomy and the product for use in the face
  • If lager treatment, chemical peel, or any other procedure based on active dermal response ia considered after treatment, or before skin has healed from a procedure prior to treatment, there is a possible riak of eliciting an inflammatory reaction at the injection site



In clinical studies, Injection site responses (ISRs) observed in >5% of treated subjects Included redness, lumps/bumps, swelling, bruising, pain, tenderness, firmness, discobration, and itching. Most ISAs were mild. Adverse events reported through postmarketing surveillance outside of the United States included | inflammatory reaction, inflammatory nodule, unsatisfactory result, loas/lack of correction, allergic reaction, anxiety, vascular occlusion, Infection, dry skin, increase/decrease in sensation, and abscess.

To report an adverse reaction with SKINVIVE” by JUVÊDERM”, please call the Allergan” Product Support Department at 1-877-345-5372. Please see Directions for Use or visit for more information.

SKINVIVE” by JUVÉDERM” is available only by a licensed physician or property licensed practitioner.